英文名稱 | Finerenone (BAY94-8862) |
---|---|
中文名稱 | 非奈利酮 |
CAS號 | 1050477-31-0 |
分子式 | C21H22N4O3 |
分子量 | 378.60 |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Finerenone (BAY94-8862) |
---|---|
中文名稱 | 非奈利酮 |
CAS號 | 1050477-31-0 |
分子式 | C21H22N4O3 |
分子量 | 378.60 |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862) displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).