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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
5 mg	3-5days	￥568.00	登錄后可見	- +
10 mg	3-5days	￥986.00	登錄后可見	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

5 mg

3-5days

￥568.00

登錄后可見

- +

10 mg

3-5days

￥986.00

登錄后可見

- +

基本信息

英文名稱	JNJ-38877605 \| JNJ 38877605
中文名稱	6-[二氟[6-(1-甲基-1H-吡唑-4-基)-1,2,4-三唑并[4,3-b]噠嗪-3-基]甲基]喹啉
CAS號(hào)	943540-75-8
分子式	C19H13F2N7
分子量	377.35
外觀	Off-white to light yellow powder
儲(chǔ)存條件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

產(chǎn)品詳情

JNJ-38877605 is an orally active ATP-competitive inhibitor of c-Met with an IC₅₀ of 4 nM, 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases. JNJ-38877605 inhibits c-Met phosphorylation and regulates lipid accumulation. JNJ-38877605 can be used for tumor and metabolic disease reseach.

相關(guān)文獻(xiàn)

A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.

PMID: 21500189 DOI: 10.1002/ijc.26137

PMID: 21464397 DOI: 10.1093/jnci/djr093

PMID: 35101055 PMCID: PMC8802424 DOI: 10.1186/s12964-021-00818-8

PMID: 37175792 PMCID: PMC10179087 DOI: 10.3390/ijms24098086

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CL1800

6-[二氟[6-(1-甲基-1H-吡唑-4-基)-1,2,4-三唑并[4,3-b]噠嗪-3-基]甲基]喹啉

943540-75-8 98+% 3-5days

￥568.00 5 mg

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6-[二氟[6-(1-甲基-1H-吡唑-4-基)-1,2,4-三唑并[4,3-b]噠嗪-3-基]甲基]喹啉

JNJ-38877605 | JNJ 38877605

化學(xué)品安全說(shuō)明書(MSDS)