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MMAF hydrochloride

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MMAF Hydrochloride;Monomethylauristatin F Hydrochloride

產(chǎn)品編號(hào):CL1348A CAS No.:1415246-68-2 MDLNo: 分子式:C39H66ClN5O8 分子量:768.42
規(guī)格 庫(kù)存 目錄價(jià) 會(huì)員專享價(jià) 數(shù)量
5 mg 3-5days ¥800.00 登錄后可見(jiàn)
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10 mg 3-5days ¥1300.00 登錄后可見(jiàn)
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25 mg 3-5days ¥2000.00 登錄后可見(jiàn)
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基本信息
英文名稱 MMAF Hydrochloride;Monomethylauristatin F Hydrochloride
中文名稱MMAF hydrochloride
CAS號(hào)1415246-68-2
分子式C39H66ClN5O8
分子量768.42
外觀White to off-white powder
儲(chǔ)存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Monomethyl auristatin F (MMAF) HCl is a highly potent tubulin inhibitor and an antineoplastic agent used as a warhead in ADCs (antibody-drug conjugates) such as vorsetuzumab mafodotin and SGN-CD19A. Mafodotin is the term used in International Nonproprietary Names for MMAF-antibody-conjugates to describe MMAF along with its antibody-binding structure. As opposed to auristatin F, which has two methyl substituents in its N-terminal amino group, MMAF is actually desmethyl-auristatin F.

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