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規(guī)格	庫(kù)存	目錄價(jià)	會(huì)員專享價(jià)	數(shù)量
5 mg	3-5days	￥358.00	登錄后可見(jiàn)	- +
10 mg	3-5days	￥548.00	登錄后可見(jiàn)	- +
25 mg	3-5days	￥698.00	登錄后可見(jiàn)	- +

規(guī)格

庫(kù)存

目錄價(jià)

會(huì)員專享價(jià)

數(shù)量

5 mg

3-5days

￥358.00

登錄后可見(jiàn)

- +

10 mg

3-5days

￥548.00

登錄后可見(jiàn)

- +

25 mg

3-5days

￥698.00

登錄后可見(jiàn)

- +

基本信息

英文名稱	LY294002 \| NSC 697286 \| SF 1101
中文名稱	LY294002 \| NSC 697286 \| SF 1101
CAS號(hào)	154447-36-6
分子式	C19H17NO3
分子量	307.34
外觀	White to yellow powder
儲(chǔ)存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產(chǎn)品詳情

LY294002, a morpholine-containing compound designed based on the flavonoid quercetin, is a potent and cell-permeable PI3K inhibitor, inhibiting PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM in cell-free assays, respectively. Additionally, it inhibits BET (for example, BRD2, BRD3, and BRD4). It is more stable in solutions than the PI3K inhibitor Wortmannin. By acting on the ATP binding site of the catalytic subunit of PI3K, LY294002 is selective against p110α, p110β, p110γ and p110δ.

相關(guān)文獻(xiàn)

Exploring the specificity of the PI3K family inhibitor LY294002.

Biochem J. 2007 May 15;404(1):15-21.

PMID: 17362206 PMCID: PMC1896275 DOI: 10.1042/BJ20070003

PMID: 23386830 PMCID: PMC3560216 DOI: 10.3389/fphar.2013.00005

PMID: 30456785 DOI: 10.1111/and.13196

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