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無水多西他賽

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Docetaxel Anhydrous

產(chǎn)品編號:CL1064 CAS No.:114977-28-5 MDLNo: 分子式:C43H53NO14 分子量:807.88
規(guī)格 庫存 目錄價 會員專享價 數(shù)量
100 mg In-stock ¥150.00 登錄后可見
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200 mg In-stock ¥250.00 登錄后可見
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500 mg In-stock ¥450.00 登錄后可見
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基本信息
英文名稱 Docetaxel Anhydrous
中文名稱無水多西他賽
CAS號114977-28-5
分子式C43H53NO14
分子量807.88
外觀White or almost white, crystalline, hygroscopic powder
儲存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

      Docetaxel, an analog of paclitaxel, is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules.    


     Docetaxel is a microtubule-stabilizing agent and a semisynthetic derivative of paclitaxel.It promotes microtubule assembly in a cell-free assay when used at a concentration of 20 μM and is cytotoxic to J774.2 cells (EC50 = 0.05 μM).In vivo, docetaxel inhibits tumor growth in several cancer models, including B16 murine melanoma and P388 murine leukemia models. Formulations containing docetaxel have been used in the treatment of head and neck, breast, and non-small cell lung cancer, gastric adenocarcinoma, and castration-resistant prostate cance


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