英文名稱 | Tivozanib (AV-951) |
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中文名稱 | 替沃扎尼 |
CAS號(hào) | 475108-18-0 |
分子式 | C22H19ClN4O5 |
分子量 | 454.86 |
外觀 | Light brown to brown powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
規(guī)格 | 庫(kù)存 | 目錄價(jià) | 會(huì)員專享價(jià) | 數(shù)量 | |
---|---|---|---|---|---|
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英文名稱 | Tivozanib (AV-951) |
---|---|
中文名稱 | 替沃扎尼 |
CAS號(hào) | 475108-18-0 |
分子式 | C22H19ClN4O5 |
分子量 | 454.86 |
外觀 | Light brown to brown powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Tivozanib is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.